Structure-activity relationships (SAR) analysis plays a vital role in drug discovery. By altering the chemical structure of a lead compound and measuring the resulting biological activity, researchers identify the key structural features responsible for efficacy. This knowledge informs further optimization of novel therapeutic agents with improved

Pharmacological profiling represents a crucial/essential/fundamental step in the development/synthesis/design of novel drug candidates. This process involves/encompasses/includes a comprehensive/thorough/systematic assessment of a drug's pharmacological/therapeutic/biochemical properties, aiming to elucidate/determine/identify its mechanism of acti